Grade And Help On 1900 Issue 25 Cent Dominion Of Canada Fractional

I am no expert on grading but I would call this VG+ to Fine. In fact, I'd say its might even be Fine (rather than VG) b/c there is very little design missing (except where there are very visible dark/soiled creases). (This is much better than white paper on the creases which demonstrates the note was washed).

Yours is therefore "original" which is a big plus for its age. The main issue is the heavy toning (darkening of paper from age) & soiling plus the large ink spots (those 2 large spots look like old teller's stamps/possibly cancellation marks to me). I was taught that you don't subtract the grade level but just mention the issues (which subtract value).

Hard to say exactly what caused the black spots, they may be some
sort of a tellers stamp but whatever the cause, they would have been
applied after the note was printed so they would be considered damage.