Will Coins Be Replaced With Paper Money Some Day ?

If coins were eliminated altogether,(perish the thought !), What paper money denominations would make the most sense ? If the US used paper money only, Keeping the $1, 5, 10, 20 & $100, ( eliminate the $50 - Than add a 25 cent full size banknote to replace the quarter. Eliminating the cent,(as Canada has done), add a full size 5 cent note (Americans would not want small size notes). Or round to nearest dime & use only a 10 cent and 25 cent note, as half dollars are rarely used & if Canada rounds to nearest nickel, why not nearest dime ? Just thinking.