Fully agree with the idea of starting two sets ... one from circulation to get you going and whatever MS coins you choose to acquire.
My Jefferson set is all CRH found ... complete 1938 - 2017 minus the 2017-D which will eventually show up here on the East coast.
It took a LOT of coins searched to complete the set ... not saying that is for you ... simply suggesting a roll found start is a nice way to get going.