Alright, I'm Pretty Worried About This.

No significant results after 2 hours. Overnight soak?

Good results with other coins even after 30 minutes. Some moron tried to clean a 1909-S dime in VF30+ instead of dipping it in acetone like its supposed to be. So, sadly, not the $200+ coin I hoped, but I paid $40 for it.

I agree with the first post about acetone. Acetone will not affect the toning; it will not react with the metal. It WILL react with PVC if that's the problem, and also will lift off oils and other potentially harmful chemicals without affecting the integrity of the coin, its toning, its surface, or any other thing important, but will get rid of a lot of other dirt, oil and crap that you don't want on the coin in the first place. Let the coin dry, which won't take long because acetone evaporates quickly.
As for rubber or plastic tongs, NO! Use your fingers, for God's sake. This coin isn't a virgin! If you want to use something between you and the coin (if it were BU), DON'T use rubber or anything plastic (one of my first high school chemistry experiments was destroying the plastic barrel of my prize Parker pen when it rolled into the acetone I spilled); silicon gloves will work.

All coins exposed to Acetone explode in 5 seconds.
JOKING of course. As noted already this is not considered cleaning. You could find out virtually many stories about the usage of Acetone by using the SEARCH thing at the top of the page. You would be amazed at how much this has been discussed.
One last warning. Watch out for breathing those vapors.
For information as to those possible problems you may want to try the ATSDR web site. Agency for Toxic Substnces & Disease Registry.