NGC Or PCGS

PCGS has enjoyed a reputation for being conservative in grading, so, like Tights said, the perception among knowledgeable slab purchasers is that there's a better chance of the grade being "correct".

In addition, the PCGS fans seem to be a bit elitist in certain ways. I don't know if I can explain this right, but, since NGC has the restoration service (NCS) and NCS will slab "problem" coins, the PCGS guys seem to think that PCGS is better because they refuse to slab any coin with any kind of problem (cleaned, damaged, corroded, rim dings, etc.) I have seen coins that PCGS body-bagged for rather miniscule defects, and a few old coppers they refused to slab because of supposed non-original surfaces. I think they were WAY off the mark on several of these coins. I guess that is a pretty good indication that PCGS is more conservative.

NGC typically has better turnaround times than PCGS, and, IMHO, NGC is better at grading Darkside material (foreign coins) than PCGS. Also, NGC will accept submissions directly if you are a member of ANA. I see that as a bonus.

All in all, it really depends on what you want. If you're a speculator or investor looking for the best profit potential, PCGS is probably going to be your choice.

There is a coin shop that I go to sometimes. He doesn't care what slab it's in. He will buy the grade HE THINKS IT IS. pcgs,anacs,ngc,pci,abcd.....it doesn't matter. I asked if He bought a pcgs 65 coin from me and I agreed to sell it at 64 money (yeah right) because thet's how he grades it, What would he sell it for in his case. As a 64 marked up a bit or as a 65 as in the holder. He said he would sell it as the grade he bought it for.
I wish I knew for sure.