If you have no addtional usage for solutions like Acetone, don't bother with that stuff. Note your coin was only $4. The average can of Acetone is about $3 to $5. To use a few ounces and then have it sit around for years, makes little CENTS you know. And too since you REALLY don't know what that discoloration is, Acetone may have no effect so more money wasted. If you haven't taken the coin out of the slab by now, you may want to take it out and put into another similar one or just a plastic flip. I'd leave it alone though. Again, a $4 purchase is just not worth a lot of trouble, cost, time and/or the cost of even a new plastic holder. Put it in a zip lock bag and forget it. Or run some cheap plastic glue along the edges to seal it more. However, even plstic glue would cost a few dollars and again, not worth a $4 coins problems.