Money, What makes these errors is one portion of the print touching another. This is the key to these.
As per misalignment by itself -- No one is currently paying a premium IF it does not affect something else on the note. A lot ebayers are selling notes where it's shifted up or down to the side etc and calling it misalignments.
In the samples I posted you will see the green treasury seal is touching or is over printed "washington D C" and the FRB district number is touching / overprinted the "right" front plate number on sn 29 and 30.
Technically SN 24 and 27 are NOT errors and SN 25 is a borderline case. These only make sense when you see them in sequence.

Hope this answers your question.