Some solid advice given here.
My general rule of thumb is to keep everything 1953 and earlier, P only for 1954-59, and after 60 only if XF-BU. A couple dozen boxes got me everything at face value except for the 1939-D and a few
War Nickels; I forget which ones.
I haven't seen it mentioned, but 1955 and 58 P (AKA plain) are semi-key dates and actually very hard to find.
1971 through 1986 or so are also very tough in high grades; I would say that the 70s are the toughest of all!
If you are going through them anyways, I would recommend filling an album of "keepers" and also keeping a pile on the side for
ebay fodder. You will come out well ahead of selling and shipping costs if you list a big lot of pre-1960 nickels.