To complete the answer
The series (2006) changes when the Secretary of the Treasury changes
The suffix (A) changes when the Treasurer of the Unites States changes
Quoting treasury.gov:
Jacob J. Lew
Secretary of the Treasury
Jack Lew was confirmed by the United States Senate on February 27, 2013, to serve as the 76th Secretary of the Treasury. Secretary Lew previously served as White House Chief of Staff. Prior to that role, Lew was the Director of the Office of Management and Budget (OMB), a position he also held in President Clinton's Cabinet from 1998 to 2001. Before returning to OMB in 2010, Lew first joined the Obama Administration as Deputy Secretary of State for Management and Resources.
Rosie Rios serves as the 43rd Treasurer of the United States. She has direct oversight over the U.S. Mint, the Bureau of Engraving and Printing and FortKnox and is a key liaison with the Federal Reserve. In addition, the Treasurer serves as a senior advisor to the Secretary in the areas of community development and public engagement. She is especially passionate about supporting Women in Finance and issues of Main Street in the economic recovery.
Prior to her confirmation as Treasurer, Rios worked at MacFarlane Partners, where she was Managing Director of Investments. Working with MacFarlane Partners' development and global capital partners, Rios played a central role in facilitating equity transactions for large mixed-use development projects in major urban areas. In November of 2008, Rios took a leave of absence from MacFarlane Partners to serve on the Treasury/Federal Reserve Transition Team and is a graduate of Harvard University.
http://www.coincommunity.com/us_1_dollar_notes/So were Mr. Lew to resign the next bills would be series 2014. But were Ms. Rios to resign the next bills would be series 2013A.
There is also the recent precedent of the $100 bills where the original printing (2009) is in storage to be inspected for the printing issues, while the reprint (2009A) has been released. And thus denco7's statement is partly correct.
It gets complex because they don't always print every denomination - see
http://www.uspapermoney.info/serials/
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