As a general rule, most notes from the larger cities do not command the premium that a note does from a smaller town.
You also had the larger banks from the larger cities that issued more high denominations than the banks did from the smaller towns. So, if you are collecting types then sometimes the larger towns are the best way to go for the high denominations.
Before committing to buying a note do your homework and see what like notes have sold for. Heritage (ha.com) has a good database for reference. To see HA prices realized at auction you have to register for an account (but it is free). You can also search
ebay items sold and get some ideas, too.
Whatever way you decide to collect do your homework and get the most value for your money.