Grading A Coin With A Slight Obverse Misalignment

Very interesting question and I'm surprised no one has replied with an answer. I would say no, since MS-70 means a perfect coin. A coin can't be perfect, if the dies were misaligned to make the rim be imperfect. Which is true for all error coins.

And what about variety coins? Is a variety coin considered perfect? Like an RPM? I would say no, since the person striking the hammer didn't hit it correctly to make a perfect mintmark.

But what about other varieties, like the Wide AM?

You contradict yourself in the last 2 sentences. But a Wide AM is a variety that can be an MS-70 though, since it is just a design variety and not an error with the coin.