Depends on the coin. I'm partial to NGC. As posted above, PCGS can can bring better value to certain coins. The only thing I would consider when submitting coins to either is that any signs of cleaning marks, rim damage, corrosion, to name a few, will yield a "range" grade which for all intensive purposes is an ungraded coin. If you're partial to US TPGs, ANACS will "detail" grade damaged coins. Although you'll often read comments on these forums that NGC/PCGS tends to be more relaxed on grading Canadian coins, I haven't found that to be a consistent theory. Does it happen? I'm sure it does. Does it happen 100% percent of the time? Absolutely not.