Ok I will answer your questions in the order they were asked in the best possible way I know how
Question 1: This all depends on if you are selling,buying or just doing it for yourself. PCGS seems to sell for more money (especially since you mentioned Moderns, PCGS MS/PF-70 will sell for multiple times what a NGC of the same grade will sell for). If you are doing it just for yourself I would probably go with ANACS myself for a few reasons, one is they are highly respected and even though they don't sell for as much in the retail world I have seen some ANACS (especially recent slabs) that are graded tighter than NGC and PCGS coins of the same series.
Question 2: If you want to send to PCGS or NGC you will either have to join their collectors society(NGC) or Collectors Club(PCGS) to submit coins or find a dealer you trust that has a dealers membership. Again with ANACS you do not have to join any club to submit coins, anyone can do it. Another thing, if you are in the ANA you can submit coins to NGC through the ANA submission form without having to join Collectors Society
Question 3: The price of the submission is considered on the value of the coins submitted and the amount of coins submitted on the same invoice (usually there is a minimum amount of coins on the invoice that can be sent in to get the lowest rate)
Question 4: First strike is a term used by the grading companies which really means absolutely nothing to real collectors (or the US Mint) as was stated in a press release addressing this issue). The only way a coin could have ever been designated as a First Strike coin is if the sealed box that the coins came to you was sent to the grading company, in other words if you opened the box when it came to you it is no longer available to receive a First Strike designation
Question 1: This all depends on if you are selling,buying or just doing it for yourself. PCGS seems to sell for more money (especially since you mentioned Moderns, PCGS MS/PF-70 will sell for multiple times what a NGC of the same grade will sell for). If you are doing it just for yourself I would probably go with ANACS myself for a few reasons, one is they are highly respected and even though they don't sell for as much in the retail world I have seen some ANACS (especially recent slabs) that are graded tighter than NGC and PCGS coins of the same series.
Question 2: If you want to send to PCGS or NGC you will either have to join their collectors society(NGC) or Collectors Club(PCGS) to submit coins or find a dealer you trust that has a dealers membership. Again with ANACS you do not have to join any club to submit coins, anyone can do it. Another thing, if you are in the ANA you can submit coins to NGC through the ANA submission form without having to join Collectors Society
Question 3: The price of the submission is considered on the value of the coins submitted and the amount of coins submitted on the same invoice (usually there is a minimum amount of coins on the invoice that can be sent in to get the lowest rate)
Question 4: First strike is a term used by the grading companies which really means absolutely nothing to real collectors (or the US Mint) as was stated in a press release addressing this issue). The only way a coin could have ever been designated as a First Strike coin is if the sealed box that the coins came to you was sent to the grading company, in other words if you opened the box when it came to you it is no longer available to receive a First Strike designation

















