Looks like a partly chipped die on the part that makes the letter E. We see them a bunch on cents, so can't imagine much of a premium on nickels either. By the way, I'll recommend to the mods that your thread be moved over to a spot where others will be more likly to weigh in on it.
"If you climb a good tree, you get a push." -----Ghanaian proverb
"The danger we all now face is distinguishing between what is authentic and what is performed." -----King Adz
That's called a Die Chip. That happens when a small piece of metal chips out of the die, causing a raised blob to appear on coins struck. Although, these Die Chips are common on Nickels and doesn't command a premium, if any.
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