Many things should be considered. For one thing how fast do you want to get rid of them? How much trouble do you expect getting rid of them? How much money do you expect for them?
Lots of questions such as those. To just get rid of them you may want to offer them to forum members here. You may want to just go to a coin shop and see what they offer for all of them. Don't forget if you use
ebay it will take time and you may never get rid of all of them and lots of time and possibly probems. You could look up on Google coin shows and your state. If you find some you could go to one and see what the dealers would offer you for the entire collection or you could rent a table and attempt to sell them there.
Or you could have a YN type giveaway on this or other coin forums where you just give some to YN's. If you do that you should stipulate an age group such as from 5 to 15 or something like that.
That is how I got rid of masses of excessive duplicates a few years ago.