Another way of thinking about it is like this. If you found a $1 quad note you might be able to sell it for $5 and receive a premium of four dollars. On a $100 note if the premium is four dollar... why bother. When people first start to collect serials they make the mistake thinking "if that $1 note is worth five times as much then the $100 must really be worth something!" In fact it is the opposite. The $1 is worth 500% and the $100 is basically worthless.
Now don't get me wrong, a really fancy serial like a solid or ladder do carry a premium on larger notes, just not the run of the mill stuff.