Keep the nice ones, sell the rest. Unless you're in love with the series, that is far and away the best course of action.
My Registry set is the product of several years of work, and I've hit the price ceiling for the most part (where gaining Registry ranks becomes financially prohibitive.) But I would not have been able to keep interest if it had some circulated coins in the mix. On the other hand, a full set of circulated dates is reasonably affordable, whether you choose AG or AU or somewhere in between, with even the keys/majors (1932-S, 1932-D, 1934-D, 1935-D, 1936-D) remaining well under $1000 in high AU.
I do think the series has upside, but only in high grades apart from the keys. A lot of collectors have yet to wake up to how truly scarce some of the date and MM combinations are in grades at and above 65. Even with Gem Uncirculated coins being saved by the roll in the 40s-60s, most of what comes out of those rolls today is found with bag marks or nicks or other grade-lowering issues. I don't think there is much potential in the 63 and below grades, excepting the "Big 5" keys/majors, the major
DDO varieties, and the two 1950 OMM's which are scarce in any grade.
Prices for even the Uncirculated coins have been depressed at MS65 and lower thanks to the discovery of large roll hoards like the Omaha Bank Hoard, which pretty much saturated the market with roll-fresh BU Roosies, Washingtons & Jeffersons. However, those hoard coins have mostly been absorbed, and prices have stabilized and I think there is room for growth.
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